Endoscopic Hemostasis Devices Market Report: Market Size & Forecast 2026

The endoscopic hemostasis devices market encompasses instruments designed to achieve hemostasis during endoscopic procedures, most commonly used to treat upper gastrointestinal bleeding including non-variceal bleeding. The global market is valued at approximately $2.3 billion in 2025, with steady expansion driven by clinical demand for effective, minimally invasive alternatives to surgical intervention. Product categories include through-the-scope clips, over-the-scope clips, thermal devices, and topical hemostatic agents including sprays and powders.

• •Market valued at approximately $2.3 billion in 2025 with 5.8% annual growth projected
• •Primary clinical applications include non-variceal upper gastrointestinal bleeding management
• •Product categories span mechanical clips, thermal coagulation, and topical hemostatic agents

Rising prevalence of gastrointestinal disorders, an aging global population, and increasing adoption of endoscopic over surgical approaches are fueling market expansion. Advancements in device design, including over-the-scope clip mechanisms and novel topical agents, are expanding the range of treatable bleeding scenarios with improved safety and efficacy profiles. Integration of artificial intelligence into hemostatic decision-making is beginning to influence procedural adoption and clinical outcomes.

• •Aging populations and rising gastrointestinal disease burden increase procedural volume
• •Novel over-the-scope clips and peptide-based hemostatic sprays broaden clinical applicability
• •AI-assisted hemostatic decision-making supports procedural optimization and adoption

The market is segmented primarily by device modality, including mechanical clips, thermal devices, and topical hemostatic agents such as spray-based formulations. Geographic distribution reflects widespread adoption across North America, Europe, and the Asia-Pacific region, where healthcare infrastructure and procedural volume vary. Topical hemostatic spray devices and emerging plant-based polysaccharide sprays represent a notable segment gaining clinical attention for their ease of application across irregular wound surfaces.

• •Segments include mechanical clips (through-the-scope and over-the-scope), thermal devices, and topical hemostatic sprays
• •Topical hemostatic agents including spray formulations are evaluated for clinical performance across endoscopic applications
• •Self-assembling peptide and plant-based polysaccharide sprays are emerging as distinct product categories

What are the recent trends and outlook?

The market is trending toward broader adoption of topical hemostatic agents, including spray-based formulations that offer advantages over mechanical clips in certain bleeding scenarios. Emerging technologies such as self-assembling peptides and plant-based polysaccharide sprays demonstrate the potential for improved hemostatic efficacy with simplified deployment. AI-assisted endoscopic decision support is expected to further influence procedural adoption and device utilization patterns in coming years.

• •Topical hemostatic sprays and novel peptide-based agents are gaining clinical adoption relative to traditional mechanical methods
• •Emerging plant-based polysaccharide and self-assembling peptide sprays are at various stages of clinical evaluation
• •AI-driven hemostatic decision-making tools are expected to shape future procedural workflows and device demand